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KMID : 1103720130680020099
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Journal of the Korean Society of Radiology
2013 Volume.68 No. 2 p.99 ~ p.106
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CT Findings of Solitary Pulmonary Nodules Less than 8 mm to Differentiate the Malignant and Benign
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Yoon Ki-Woong
Jin Gong-Yong
Han Young-Min
Kim Eun-Young
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Abstract
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Purpose: We assessed CT features of the solitary pulmonary nodules (SPNs) smaller than 8 mm to evaluate the differences between the benign and malignant nodules.
Materials and Methods: The study included 113 patients (66 male, 47 female, age range: 33-79 years) with SPNs smaller than 8 mm. Mean diameter of SPN on CT was 4.95 ± 1.19 cm; benign, 4.91 ± 1.24 mm; and malignant, 6.09 ± 1.01 mm. Of the 113 nodules, there were 23 (20.4%) malignant nodules and 90 (79.6%) benign nodules. The CT findings (size, shape, margin, density) of SPNs were analyzed. The statistical differences of the malignant and benign nodules were analyzed by χ2 test.
Results: The differences of the benign and malignant nodules were in the margin and density. In the margins, spiculation and lobulation occurred with a significantly higher frequency in the malignant nodules (spiculated: 10/23, lobulated: 7/23) than the benign nodules (spiculated: 20/90, lobulated: 0/90) (p < 0.001). In the mixed or pure ground glass attenuation (14/23), the malignancy rates were significantly higher than the solid nodules (p < 0.001). In the mixed and pure attenuation, a lobulated or spiculated margin (12/14) was associated with a higher risk of malignancy (p = 0.005).
Conclusion: In smaller than 8 mm nodules, the predictive CT findings of malignancy were spiculated or lobulated margin and mixed or pure attenuation.
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KEYWORD
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Lung Neoplasms, Solitary Pulmonary Nodule, Multidetector Computed Tomography
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